Can You Overdose on Cannabis?

No, you cannot overdose on cannabis alone (unless you consume extreme amounts), although it may contribute to overdose via interactions with other medicines and drugs. For example, mixing marijuana with alcohol is generally a bad idea. Meanwhile, mixing high CBD with benzodiazepines may cause problems, as both work on CB2 receptors in the liver. You can also have a sort of “temporary overdose” (aka “whiteying/white-out” or “getting a greenie”), although this is short-lived and recovered from quite easily with food, water and/or rest.